Natural Longevity Solution
Actiful® was developed as the perfect synergy of citrus extracts – hesperidin from sweet orange and punicalagin from pomegranate.
This dynamic combination works in harmony to deliver a natural solution for increased energy, vitality, and long-term wellness.
With Actiful® Body & Mind are in sync!
Clinically proven benefits
Unique mode of action
Stimulant-free
Low daily dose of 600-700 mg
Healthy Aging, Cellular Health and Longevity
Longevity Boost
To maintain overall well-being at on older age, it is important to pay attention to various lifestyle factors like physical activity, diet and supplement intake.
A randomized, placebo-controlled trial (N=36) showed that just 4 weeks of Actiful® intake resulted in significantly increased handgrip strength and improved quality of life in seniors 60+ years of age. The quality of life questionnaire included domains like memory, thinking, learning and concentration.
Significant improvement in psychological function including thinking, memory, learning and concentration.
* significant increase (p=0.042) after 4 weeks daily Actiful® intake, compared to placebo.
Cellular Health Backed-up by Science
The second study with Actiful® revealed its ability to support cellular health and vitality. The RCT was performed in seniors and the aim was to investigate the effect of Actiful® on methylglyoxal (MGO) levels in the blood – a key marker of cellular dysfunction.
MGO is a precursor to advanced glycation end products (AGEs), associated with cell dysfunction and eventual apoptosis. MGO reduction translates to scavenging of cellular waste and therefore improved cellular function and cellular longevity.
Our study showed a significant 9,8% reduction of MGO after just 4 weeks Actiful® intake, showcasing its potential as a key ingredient in healthy aging and longevity products.
MGO plasma concentration at baseline and after 4 weeks.
*significant decrease after Actiful® intake compared to placebo (p=0.042).
Physical and mental well-being in elderly
The benefits of Actiful® were also investigated in a randomized clinical trial with senior subjects 60+.
The study revealed that Actiful® consumption results in improved physical performance and better quality of life, two crucial factors in successful ageing.
Specifically, after 4 weeks of supplementation, strength and psychological functions improved significantly in the supplementation group.
Dual action effect
Citrus – Energy
- Blocks leakage of protons (H+) in the mitochondria
- Higher levels of H+, increases respiration ability of mitochondria
- More respiration = enhanced ATP production = more energy
Citrus – Blood flow
- Activates phosphorylation of Endothelial Nitric Oxide Synthase (eNOS), the key enzyme for Nitric Oxide (NO) synthesis
- More NO = enhanced blood flow (vasodilation)
- Greater oxygen availability for muscle cells = more energy (ATP)
Pomegranate – blood flow
- High levels of nitrate (substrate for NO) = increases NO production = enhances blood flow
- Strong anti-oxidant
Find out more about the sustainable way we use immature oranges for our citrus extracts’
White paper
Download the white paper and discover the scientific evidence around Actiful®.
Researched & developed by Solabia Nutrition
Actiful® was researched and developed by Solabia Nutrition, a life science company that develops health ingredients for functional foods, clinical nutrition and dietary supplements.
Solabia Nutrition focuses on the core mission of bringing nutritional products backed up by real science to consumers, helping them perform better and improve their health and well-being.
Find out more about Solabia Nutrition, visit the website